Shockwave Therapy Clinical Studies
Extracorporeal shockwave therapy (ESWT) ameliorates healing of tibial fracture non-union unresponsive to conventional therapy
Tibial non-unions are common cause of demanding revision surgeries and are associated with a significant impact on patients’ quality of life and health care costs. Extracorporeal shockwave therapy (ESWT) has been shown to improve osseous healing in vitro and in...
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Shock Wave Therapy and Fracture Healing: A Bayesian Prediction Model
Title of study: Development of a Prognostic Naïve Bayesian Classifier for Successful Treatment of Nonunions Authors: Alexander Stojadinovic, MD, Benjamin Kyle Potter, MD, John Eberhardt, BA, Scott B. Shawen, MD, Romney C. Andersen, MD, Jonathan A. Forsberg, MD, Clay Shwery,...
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Shockwaves Prevent From Heart Failure After Acute Myocardial Ischaemia via RNA/Protein Complexes
Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3). The antimicrobial peptide LL37 gets released by mechanical stress and is known to form complexes with nucleic acids thus activating Toll-like receptors. We...
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Shock Wave Therapy Improves Cardiac Function in a Model of Chronic Ischemic Heart Failure: Evidence for a Mechanism Involving VEGF Signaling and the Extracellular Matrix
Background Mechanical stimulation of acute ischemic myocardium by shock wave therapy (SWT) is known to improve cardiac function by induction of angiogenesis. However, SWT in chronic heart failure is poorly understood. We aimed to study whether mechanical stimulation upon SWT improves heart function in...
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Shockwave Therapy Reduces Calcification of Decellularized Aortic Xenografts in Mice
Title of study: Alteration of inflammatory response by shock wave therapy leads to reduced calcification of decellularized aortic xenografts in mice Authors: Can Tepeköylü, Daniela Lobenwein, Stefan Blunder, Radoslaw Kozaryn, Marion Dietl, Paul Ritschl, Elisabeth J Pechriggl, Michael J F...
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Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle
Aims Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for the treatment of ischaemic heart or lim disease. Despite promising results in preclinical and clinical trials, the exact mechanism of action remains unknown. Toll-like...
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Shock wave treatment induces angiogenesis and mobilizes endogenous cd31/cd34-positive endothelial cells in a hindlimb ischemia model: implications for angiogenesis and vasculogenesis
Shock waves have been shown to induce recruitment of intravenously injected endothelial progenitor cells to ischemic hind limbs in rats. We hypothesized that shock wave treatment as sole therapy would induce angiogenesis in this ischemia model and would lead to...
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Accelerated Healing of 2nd-Degree Burns with Shockwave Therapy
Title: Prospective Randomized Phase II Trial of Accelerated Reepithelialization of Superficial Second-Degree Burn Wounds Using Extracorporeal Shock Wave Therapy Authors: Christian Ottomann, MD,∗ Alexander Stojadinovic, MD, FACS, Philip T. Lavin, PhD, Francis H. Gannon, MD, Michael H. Heggeness, MD, Richard...
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Effects of Low-Energy Shock Waves on Oral Bacteria
Title: Effects of low-energy shock waves on oral bacteria Authors: K F Novak, M Govindaswami, J L Ebersole, W Schaden, N House, M J Novak Low-energy shock wave therapy (ESWT) has been found to be effective in promoting wound healing...
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The Influence of Shockwave Therapy on Orthodontic Tooth Movement Induced in the Rat
The application of orthodontic force evokes an inflammatory reaction resulting in tooth movement. Shockwave therapy might have an effect on both inflammatory and periodonal ligament cytokine profiles. Our aim was to evaluate the fluctuations of different inflammatory cytokines after orthodontic...
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