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Wound Care Research

Shockwave Therapy Exhibits Significant Antibacterial Effects

Shockwave Therapy Exhibits Significant Antibacterial Effects

Title of study: Antibacterial effects of extracorporeal shock waves Authors: Ludger Gerdesmeyer, Christof von Eiff, Carsten Horn, Mark Henne, Michaela Roessner, Peter Diehl, Hans Gollwitzer A study conducted on the effect of extracorporeal shock-wave therapy (ESWT) on Staphylococcus aureus bacteria...
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Shock wave therapy for acute and chronic soft tissue wounds: a feasibility study

Shock wave therapy for acute and chronic soft tissue wounds: a feasibility study

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Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

Extracorporeal shock wave therapy suppresses the early proinflammatory immune response to a severe cutaneous burn injury

Thomas A Davis, Alexander Stojadinovic, Khairul Anam, Mihret Amare, Shruti Naik, George E Peoples, Douglas Tadaki, Eric A Elster Following severe burn injury, persistent inflammation perpetuated by surface eschar, bacterial colonisation and neutrophil proteolytic activity can impede normal healing and...
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Shock Waves: A New Non-Surgical Method to Treat Severe Burns

Shock Waves: A New Non-Surgical Method to Treat Severe Burns

Title: Extracorporeal shock waves, a new non-surgical method to treat severe burns Authors: Anna Arno, Oscar Garcia-Algar, Izaro Hernan, J Sancho, A Acosta, Juan Barret Extracorporeal shock wave therapy (ESWT) has been widely used in urology and orthopaedic surgery due...
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Extracorporeal Shockwave Treatment for Chronic Diabetic Foot Ulcers

Extracorporeal Shockwave Treatment for Chronic Diabetic Foot Ulcers

Title: Extracorporeal Shockwave Treatment for Chronic Diabetic Foot Ulcers Authors: Ching-Jen Wang, M.D., Yur-Ren Kuo, M.D., Ph.D., Re-Wen Wu, M.D., Rue-Tsuan Liu, M.D., Chi-Shiung Hsu, M.D., Feng-Sheng Wang, Ph.D., Kuender D. Yang, M.D. This study compared the effectiveness of two...
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Shockwave Therapy: Evidence for Soft Tissue Wound Healing

Shockwave Therapy: Evidence for Soft Tissue Wound Healing

Title: Evidence supporting extracorporeal shock wave therapy for acute and chronic soft tissue wounds Authors: Vlado Antonic, Rainer Mittermayr, Wolfgang Schaden, Alexander Stojadinovic This study focuses on the benefits of extracorporeal shockwave therapy (ESWT) in the treatment of acute and...
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​Prospective randomized phase II trial of accelerated reepithelialization

​Prospective randomized phase II trial of accelerated reepithelialization

Christian Ottomann, MD, Alexander Stojadinovic, MD, FACS,  Philip T. Lavin, PhD,§ Francis H. Gannon, MD, Michael H. Heggeness, MD, Richard Thiele, MD, Wolfgang Schaden, MD, and Bernd Hartmann, MD As extracorporeal shock wave therapy (ESWT) can enhance healing of skin...
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Extracorporeal Shockwave Therapy for Treatment of Keloid Scars

Extracorporeal Shockwave Therapy for Treatment of Keloid Scars

Title: Extracorporeal Shockwave Therapy for Treatment of Keloid Scars  Authors: Ching-Jen Wang, M.D., Jih-Yang Ko, Wen-Yi Chou, Jai-Hong Cheng, Yur-Ren Kuo Many methods of treatment were proposed for the keloids including steroid injection, surgical excision, radiation therapy, laser therapy, pressure...
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ESWT for retracting scars of the hand

ESWT for retracting scars of the hand

Department of Medical Sciences, Oral and Biotechnology, ‘‘G. D’Annunzio’’ University, Chieti, Italy;  Department of Dermatology, University of Rome Tor Vergata, Rome, Italy; Department of Plastic and Reconstructive Surgery, ‘‘Sapienza’’ University, Policlinico Umberto I, Rome, Italy;  School of Specialties in Physical...
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Shock Wave Therapy for Acute and Chronic Soft Tissue Wounds: A Feasibility Study

Shock Wave Therapy for Acute and Chronic Soft Tissue Wounds: A Feasibility Study

Title: Shock Wave Therapy for Acute and Chronic Soft Tissue Wounds: A Feasibility Study Authors: Wolfgang Schaden, M.D., Richard Thiele, M.D., Christine Kölpl, M.D., Michael Pusch, M.D., Aviram Nissan, M.D., Christopher E. Attinger, M.D., F.A.C.S., Mary E. Maniscalco-Theberge, M.D., F.A.C.S.,...
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Molecular changes in diabetics foot ulcers

Molecular changes in diabetics foot ulcers

The Department of Orthopedic Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan This study investigated the molecular changes of extracorporeal shockwave therapy (ESWT) and hyperbaric oxygen therapy (HBOT) in chronic diabetic foot ulcers....
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The influence of comorbidities – ESWT for chronic soft tissue wounds

The influence of comorbidities – ESWT for chronic soft tissue wounds

Department of Surgery, Austrian Armed Forces Hospital-Vienna, Vienna, Austria;  AUVA Trauma Center Meidling, Vienna, Austria;  Department of Radiology, Medical University of Vienna, Vienna; Department of Surgery, Medical University of Vienna, Vienna, Austria; Center of Anatomy and Cell Biology, Medical University...
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Shockwave Therapy: Reducing Tissue Necrosis & Enhancing Revascularization

Shockwave Therapy: Reducing Tissue Necrosis & Enhancing Revascularization

Title: Extracorporeal Shock Wave Therapy (ESWT) Minimizes Ischemic Tissue Necrosis Irrespective of Application Time and Promotes Tissue Revascularization by Stimulating Angiogenesis Authors: Rainer Mittermayr, MD, Joachim Hartinger, Vlado Antonic, MS, Alexandra Meinl, PhD, Sabine Pfeifer, Alexander Stojadinovic, MD, Wolfgang Schaden,...
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DermaGold® Shockwave Therapy for Wound Care: Meta-Analysis Results

DermaGold® Shockwave Therapy for Wound Care: Meta-Analysis Results

Title of study: DermaGold 100 Wound Care Meta-Analysis Author: Philip Lavin, PhD, FASA, FRAPS This study covers the effectiveness and safety of Extracorporeal Shock Wave Therapy (ESWT), specifically DermaGold and Orthowave 180, in wound care treatment. The DermaGold® wound care meta-analysis...
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Technology Assessment “Wound Care” dermagold100

Technology Assessment “Wound Care” dermagold100

MTS-Science – ​Acute wounds are caused exogenously by traumatic (e.g. mechanical, chemical, thermical) or iatrogenic (e.g. surgical) injury. In general, they are sharply limited and heal within short time without major complications. If there is no progress in healing after more than...
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The Exosome – A Naturally Secreted Nanoparticle and its Application to Wound Healing.

The Exosome – A Naturally Secreted Nanoparticle and its Application to Wound Healing.

Rani S, Ritter T – Wound healing is a complex process and often delayed in patients with underlying chronic conditions. The cost of wound care is a significant burden to the society, warranting new techniques to prompt wound healing. Several studies have...
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MSC-exosome: A novel cell-free therapy for cutaneous regeneration

MSC-exosome: A novel cell-free therapy for cutaneous regeneration

Peipei Wu, Bin Zhang, HuiShi, Hui Qian, Wenrong Xu – Cutaneous regeneration is a dynamic and complex process that requires a series of coordinated interactions involving epidermal cells, dermal cells, growth factors, the extracellular matrix (ECM), nerves and blood vessels at a damaged site. Mesenchymal stromal cells...
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MTS Spark WaveTM Technology and its mechanism of action in wound management

MTS Spark WaveTM Technology and its mechanism of action in wound management

MTS-Science​  – Diabetic foot ulcers are one of the most serious complications of diabetes mellitus and are associated with high morbidity as well as mortality. They often predate amputation of the feet and / or the lower limbs and therefore have...
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Preoperative Shockwave Therapy Improves Wound Healing – (Med Esthetics Mag​)

Preoperative Shockwave Therapy Improves Wound Healing – (Med Esthetics Mag​)

A prospective, randomized, double‐blinded, controlled pilot trial of 24 abdominoplasty patients revealed that preoperative application of extracorporeal shockwave therapy (ESWT) reduces post-surgical scar thickness and improves the appearance of scars. The study, led by Elisabeth Russe, MD, is titled “Effects...
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Shockwave Therapy Boosts Wound Healing: A Review of the Evidence

Shockwave Therapy Boosts Wound Healing: A Review of the Evidence

Title: Extracorporeal Shock Wave Therapy as an Adjunct Wound Treatment: A Systematic Review of the Literature Authors: Robert Dymarek, PhD, PT; Tomasz Halski, PhD, PT; Kuba Ptaszkowski, PhD, PT; Lucyna Slupska, PhD, PT; Prof. Joanna Rosinczuk, PhD, MSc; and Prof....
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Shockwave Therapy for Wound Healing: A Review & Analysis

Shockwave Therapy for Wound Healing: A Review & Analysis

Title: Efficacy and safety of extracorporeal shock wave therapy for acute and chronic soft tissue wounds: A systematic review and meta-analysis Authors: Li Zhang, Xiao-bing Fu, Shuo Chen, Zhan-bo Zhao, Christoph Schmitz, Chang-shui Weng This study aimed to evaluate the...
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Shockwave Therapy for Diabetic Foot Ulcers: Review and Meta-Analysis

Shockwave Therapy for Diabetic Foot Ulcers: Review and Meta-Analysis

Title: Extracorporeal Shockwave Therapy for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis Authors: Louise Helen Hitchman, Joshua P. Totty, Ali Raza, Paris Cai, George E. Smith, Daniel Carradice, Tom Wallace, Amy E. Harwood, and Ian C. Chetter Diabetic foot...
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Shockwave Therapy Reduces Wound Size by 99.9% in Elderly Patient

Shockwave Therapy Reduces Wound Size by 99.9% in Elderly Patient

Title of study: A case study on the effectiveness of DermaGold soft-focused multiwave therapy in treating an infected wound The case study focuses on an 80-year-old female patient who developed a large infected decubitus ulcer after a knee operation and...
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The Role of Spark Waves in the Management of Chronic Wounds.

The Role of Spark Waves in the Management of Chronic Wounds.

Antibiotic-resistant bacterial colonies often produce biofilms (a defensive mechanism that creates a physical protective barrier against antibiotic treatment). SWT can break up the physical biofilm barriers, thereby allowing antibiotics to gain access to the entrenched bacteria and eradicate the colony....
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Extracorporeal Shockwave Therapy (ESWT) in Skin & Aesthetic Indications

Extracorporeal Shockwave Therapy (ESWT) in Skin & Aesthetic Indications

This presentation from the 22nd International Society for Medical Shockwave Treatment (ISMST) in Beijing, China covers Extracorporeal Shockwave Therapy's (ESTW) remarkable impact on various skin conditions and aesthetic indications—from diminishing cellulite and scars to healing burn and diabetic wounds. Click...
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Shockwave Therapy Wound Healing Application: A Protocol Analysis

Shockwave Therapy Wound Healing Application: A Protocol Analysis

Title of study: Analysis of treatment protocols: application of ESWT for wound healing disorders Shockwave therapy is a non-invasive medical treatment that uses high-energy acoustic waves to stimulate healing processes in bones and soft tissues. Recent research has shown that...
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Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study

Extracorporeal Shock Wave Therapy for Digital Ulcers of Systemic Sclerosis: A Phase 2 Pilot Study

Patients with systemic sclerosis (SSc) often display Raynaud’s phenomenon and digital skin ulcers. As these ulcers are not associated with autoimmune factors or abnormal coagulation, conventional immunosuppressive therapies, vasodilators, and anticoagulants are often ineffective. Here, we used extracorporeal shock wave...
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Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shockwave lithotripsy

Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shockwave lithotripsy

CREST syndrome is a variant of systemic sclerosis, which affects a relatively small number of patients. CREST (also called limited cutaneous scleroderma) has a more favorable prognosis than the diffuse form of scleroderma. However, cutaneous calcinosis, which occurs during the...
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SoftWave Therapy® Represents a Valuable Addition in the Treatment of Hard-to-Heal Wounds

SoftWave Therapy® Represents a Valuable Addition in the Treatment of Hard-to-Heal Wounds

Prof. Hilde Beele (MD), Steven Smet, Francis Ramboer, at Ghent University Hospital faced up to the great challenge in the treatment of non-healing diabetic foot wounds and demonstrated the beneficial effect for Hard-to-Heal conditions with SoftWave Therapy. Click here to read more.
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Spark Wave® Therapy Improves Full Thickness Skin Defects

Spark Wave® Therapy Improves Full Thickness Skin Defects

Skin grafting is one of the most common treatment options for permanent replacement of lost skin and proven effective in burn patients. The procedure consists of transplantation of skin or artificial dermal replacements, and in some instances underlying tissues, harvested...
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Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

Extracorporeal shock wave therapy role in the treatment of burn patients. A systematic literature review

Extracorporeal shock wave therapy (ESWT), first described in the eighties for the treatment of urolithiasis, has also been applied in other fields such as orthopaedics and chronic wound care. Recently it has also been used in the treatment of burns...
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Shockwave Therapy Heals Dystrophic Calcinosis Cutis Ulcer

Shockwave Therapy Heals Dystrophic Calcinosis Cutis Ulcer

Title of study: Effectiveness of Extracorporeal Shock Wave Lithotripsy to Treat Dystrophic Calcinosis Cutis Ulcers Authors: A.M. Delgado-Márqueza, M. Carmonab, F. Vanaclochaa, C. Postigoa In this case study, a 78-year-old woman with various medical conditions, including lupus erythematosus and scleroderma,...
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Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

(Alexandra Aicher, MD; Christopher Heeschen, MD; Ken-ichiro Sasaki, MD; Carmen Urbich, PhD; Andreas M. Zeiher, MD; Stefanie Dimmeler, PhD) – Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of ischemic tissue. Enhanced tissue expression of...
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Prophylactic Low-Energy Shock Wave Therapy Improves Wound Healing After Vein Harvesting for Coronary Artery Bypass Graft Surgery: A Prospective, Randomized Trial

Prophylactic Low-Energy Shock Wave Therapy Improves Wound Healing After Vein Harvesting for Coronary Artery Bypass Graft Surgery: A Prospective, Randomized Trial

Wound healing disorders after vein harvesting for coronary artery bypass graft surgery increase morbidity and lower patient satisfaction. Low-energy shock wave therapy (SWT) reportedly improves healing of diabetic and vascular ulcers by overexpression of vascular endothelial growth fractor and downregulation...
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Serum Proteomic Analysis of Extracorporeal Shock Wave Therapy–Enhanced Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Model

Serum Proteomic Analysis of Extracorporeal Shock Wave Therapy–Enhanced Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Model

This study investigated the plasma protein expression in the extracorporeal shock wave therapy group and diabetic controls using proteomic study. A dorsal skin defect (6 × 5 cm) in a streptozotocin-induced diabetic Wistar rat model was used. Diabetic rats receiving...
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Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

Shockwave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying the beneficial effects of shockwaves have not yet been fully revealed. Since cell proliferation is a major requirement in the wound healing cascade, we used in...
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Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

Randomized control of extracorporeal shock wave therapy versus placebo for chronic decubitus ulceration

Anna M Larking, Sophie Duport Institute of Neuropalliative Rehabilitation, Royal Hospital for Neuro-disability, Michael Clinton Department of Management, King’s College, Mary Hardy Practice Development, Royal Hospital for Neurodisability and Keith Andrews Institute of Neuropalliative Rehabilitation, Royal Hospital for Neuro-disability, London, UK...
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Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

Extracorporeal shock wave therapy (ESWT) for wound healing : Technology, mechanisms, and clinical efficacy

For almost 30 years, extracorporeal shock wave therapy has been clinically implemented as an effective treatment to disintegrate urinary stones. This technology has also emerged as an effective noninvasive treatment modality for several orthopedic and traumatic indications including problematic soft...
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Prospective randomized trial of accelerated re- epithelization of skin graft donor sites using extracorporeal shock wave therapy

Prospective randomized trial of accelerated re- epithelization of skin graft donor sites using extracorporeal shock wave therapy

Background: Extracorporeal shock wave therapy may enhance revascularization and repair of healing soft tissue. Methods: Between January 2006, and September 2007, 28 patients with acute traumatic wounds and burns requiring skin grafting were randomly assigned in a 1:1 fashion to receive...
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