Shockwave Therapy Clinical Studies
Shockwave Therapy Reduces Knee Osteoarthritis Progression in Rabbits
Title: Extracorporeal shock-wave therapy reduces progression of knee osteoarthritis in rabbits by reducing nitric oxide level and chondrocyte apoptosis Authors: Zhe Zhao, Huiru Ji, Rufang Jing, Chunmei Liu, Mingbo Wang, Lei Zhai, Xiaodong Bai & Gengyan Xing This study investigated...
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Focused high‐energy extracorporeal shockwaves as supplemental treatment in a rabbit model of fracture‐related infection
Focused high‐energy extracorporeal shockwave therapy (fhESWT) is used to improve fracture healing in cases of nonunion. In addition, it has been shown to have direct antibacterial effects. We evaluated fhESWT as an adjunct to conventional treatment in a clinically relevant...
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Shockwaves prevent from heart failure after acute myocardial ischemia via RNA/protein complexes
Shock wave treatment (SWT) was shown to induce regeneration of ischaemic myocardium via Toll-like receptor 3 (TLR3). The antimicrobial peptide LL37 gets released by mechanical stress and is known to form complexes with nucleic acids thus activating Toll-like receptors. We sug- gested...
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Effect of shock waves on macrophages
Extracorporeal Shock Wave Therapy (ESWT) is broadly used as a non-surgical therapy in various diseases for its pro-angiogenic and anti-inflammatory effects. However, the molecular mechanisms translating tissue exposure to shock waves (SW) in a biological response with potential therapeutic activity...
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Lohse – Busch ISMST Presentation
High-energy ESW can destroy non myelinated nerves but afterwards there is an even faster regeneration. Click here to read more.
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Latest Basic Research Abstracts
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Shock wave as biological therapeutic tool: from mechanical stimulation to recovery and healing, through mechanotransduction
Extracorporeal Shock Wave Therapy (ESWT) is a form of “mechanotherapy”, that, from its original applications as urological lithotripsy, gained the field of musculo-skeletal diseases as Orthotripsy (mainly tendinopaties and bone regenerative disorders) and Regenerative Medicine as well. Click here to...
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Shockwave treatment enhances cell proliferation and improves wound healing by ATP release coupled extracellular signal-regulated kinase (ERK) activation
Shock wave treatment accelerates impaired wound healing in diverse clinical situations. However, the mechanisms underlying the beneficial effects of shock waves have not yet been fully revealed. Because cell proliferation is a major requirement in the wound healing cascade, we...
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Enhancing recruitment of endothelial progenitor cells
Background— Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of ischemic tissue. Enhanced tissue expression of chemoattractant factors such as stromal cell–derived factor 1 and vascular endothelial growth factor is crucial for the recruitment of...
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IVSWT Water Bath V2.0 Manual
The number of in-vitro experiments in shock wave science increases continuously. This fact reflects how important basic research findings on the cellular and sub-cellular level are for the future progress of shock wave therapy. In some very emerging fields better...
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