Shockwave Therapy Clinical Studies
The Importance of Mechanical Signals in Regulating Cellular Behavior
Title of study: Cellular Mechanotransduction: Putting All the Pieces Together Again Author: Donald E. Ingber This study delves into cellular mechanotransduction, which is the process by which cells convert mechanical signals into biochemical responses. Scientists have identified various mechanosensitive molecules...
Learn more about The Importance of Mechanical Signals in Regulating Cellular Behavior
Mesenchymal cells: Myths and reality
Mesenchymal cells (MSCs; also called mesenchymal stromal cells) have received much attention during the last two decades, at first because of their regeneration capacity and poor immunogenicity and, more recently, because of their proved immunomodulatory function. Click here to read...
Learn more about Mesenchymal cells: Myths and reality
Shock Wave Therapy Promotes Angiogenesis via Toll-like Receptor 3
Title of study: Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle Authors: Johannes Holfeld, Can Tepeköylü, Christin Reissig, Daniela Lobenwein, Bertram Scheller, Elke Kirchmair, Radoslaw Kozaryn, Karin Albrecht-Schgoer, Christoph Krapf, Karin Zins, Anja Urbschat,...
Learn more about Shock Wave Therapy Promotes Angiogenesis via Toll-like Receptor 3
Scientific Reports – Gene transfection by shock waves
Extracorporeal shock wave (SW) therapy has been studied in the transfection of naked nucleic acids into various cell lines through the process of sonoporation, a process that affects the permeation of cell membranes, which can be an effect of cavitation....
Learn more about Scientific Reports – Gene transfection by shock waves
Novel Approach to Obtain an Activated Fat Graph
One of the mainstays of facial rejuvenation strategies is volume restoration, which can be achieved by autologous fat grafting. In our novel approach, we treated the adipose tissue harvest site with extracorporeal shock wave therapy (ESWT) in order to improve...
Learn more about Novel Approach to Obtain an Activated Fat Graph
UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors
Platelet-rich plasma (PRP) and extracorporeal shockwave therapy (ESWT) are both used for the treatment of soft tissue injuries in horses. Clinically, the question has been raised whether these two therapies could be used in combination. The hypothesis of this study...
Learn more about UGA In vitro study: ESWT treatment of platelets causes increased release of growth factors
Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus
Mononuclear invasion of Langerhans islet and the ensuing insulitis triggers signal-transduction for the autoimmune mediated pancreatic beta-cell (b-cell) apoptosis that severely disrupts insulin production resulting in hyperglycemia associated with Type-1 diabetes (T1DM). Today extensive global research is being conducted to...
Learn more about Original hypothesis: Extracorporeal shockwaves as a homeostatic autoimmune restorative treatment (HART) for Type 1 diabetes mellitus
Shockwaves induce osteogenic differentiation of human mesenchymal cells through ATP release and activation of P2X7 receptors
Shockwave fractures treatment promotes bone healing of nonunion fractures. In this study, we investigated whether this effect could be due to adenosine 5’-triphosphate (ATP) release-induced differentiation of human mesenchymal cells (hMSCs) into osteoprogenitor cells. Cultured bone marrow-derived hMSCs were subjected...
Learn more about Shockwaves induce osteogenic differentiation of human mesenchymal cells through ATP release and activation of P2X7 receptors
Shockwave Therapy Enhances Stem Cell Healing Potential
Title of study: Cell biological effects of mechanical stimulations generated by focused extracorporeal shock wave applications on cultured human bone marrow stromal cells Authors: Frank Suhr, Yvonne Delhasse, Gerd Bungartz, Annette Schmidt, Kurt Pfannkuche, Wilhelm Bloch Human bone marrow stromal...
Learn more about Shockwave Therapy Enhances Stem Cell Healing Potential
Shockwave Therapy Boosts Equine Stem Cell Proliferation and Viability
Title of study: Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal cells in vitro Authors: O Raabe, K Shell, A Goessl, C Crispens, Y Delhasse, A Eva, G Scheiner-Bobis, S Wenisch, S Arnhold Researchers...
Learn more about Shockwave Therapy Boosts Equine Stem Cell Proliferation and Viability
