Title of study: Biological mechanism of shockwave in bone
Author: Jai-Hong Cheng, Ching-Jen Wang
Shockwave therapy is a non-invasive treatment that uses acoustic waves to promote healing in damaged tissue. This type of therapy, known as extracorporeal shockwave therapy (ESWT), works by inducing biological effects in living tissue through a mechanical stimulus. The therapy has shown promise in promoting tissue regeneration, wound healing, angiogenesis, bone remodeling, and anti-inflammation.
While the therapy has been used for some time, little was known about the mechanism behind its effectiveness until recently. This study investigated the molecular mechanisms involved in ESWT and explored its pre-clinical and clinical applications for treating bone disorders.
The study found that ESWT promotes biological healing processes through mechanotransduction, which is the conversion of mechanical signals into biochemical signals. This process triggers a series of cellular responses, including the activation of growth factors, cytokines, and stem cells, that promote tissue regeneration and healing.
The researchers also found that ESWT is effective in treating a range of bone disorders, including non-union fractures, osteoarthritis, and avascular necrosis. Clinical studies have shown that ESWT can improve pain and function in patients with these conditions, with minimal side effects.
Overall, this study highlights the potential of ESWT as a non-invasive and effective treatment option for tissue healing. Its ability to promote biological healing processes through a mechanical stimulus could have significant implications for the treatment of a range of conditions, particularly those related to bone and soft tissue injuries.
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